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1

Regulation of Expression of Interleukin-6 : Molecular and Clinical Studies

ANURADHA RAY, STEPHEN B. TATTER, UMA SANTHANAM, DAVID C. HELFGOTT, LESTER T. MAY, PRAVINKUMAR B. SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 661 KB

english, 1989

2

Interleukin-6: Molecular Pathophysiology.

Sehgal, Pravinkumar B.

Journal:

The Journal of Investigative Dermatology

Year:

1990

File:

PDF, 1.35 MB

1990

3

Early Ad-2 transcription units: Only promoter-proximal RNA continues to be made in the presence of DRB

Pravinkumar B. Sehgal, Nigel W. Fraser, James E. Darnell Jr.

Journal:

Year:

1979

Language:

english

File:

PDF, 612 KB

english, 1979

4

Interferon action: Two (2′-5′) (A)n synthetases specified by distinct mRNAs in Ehrlich ascites tumor cells treated with interferon

Laurent, Georges St., Yoshie, Osamu, Floyd-Smith, Georgia, Samanta, Himadri, Sehgal, Pravinkumar B., Lengyel, Peter

Journal:

Year:

1983

Language:

english

File:

PDF, 2.02 MB

english, 1983

5

Cytokines in normal and abnormal parturition: Elevated amniotic fluid interleukin-6 levels in women with premature rupture of membranes associated with intrauterine infection

Santhanam, Uma, Avila, Cecilia, Romero, Roberto, Viguet, Huguette, Ida, Nobuo, Sakurai, Shingou, Sehgal, Pravinkumar B.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

6

[Part 1: Biological Sciences] || Internal Duplication in Human α1and β1Interferons

Bruce W. Erickson, Lester T. May and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 909 KB

english, 1984

7

Human Chromosome 7 Carries the β2Interferon Gene

Pravinkumar B. Sehgal, Asher Zilberstein, Rosa-Maria Ruggieri, Lester T. May, Anne Ferguson-Smith, Doris L. Slate, Michel Revel and Frank H. Ruddle

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 793 KB

english, 1986

8

Multiple Discrete Sites for Premature RNA Chain Termination Late in Adenovirus-2 Infection: Enhancement by 5,6-dichloro-1-β -D-ribofuranosylbenzimidazole

Nigel W. Fraser, Pravinkumar B. Sehgal and James E. Darnell

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 1.42 MB

english, 1979

9

Amniotic Fluid Interleukin-6 Determinations Are of Diagnostic and Prognostic Value in Preterm Labor

ROMERO, ROBERTO, YOON, BO HYUN, KENNEY, JOHN S., GOMEZ, RICARDO, ALLISON, ANTHONY C., SEHGAL, PRAVINKUMAR B.

Journal:

American Journal of Reproductive Immunology

Year:

1993

Language:

english

File:

PDF, 1.84 MB

english, 1993

10

DRB-induced premature termination of late adenovirus transcription

Fraser, Nigel W., Sehgal, Pravinkumar B., Darnell, James E.

Journal:

Year:

1978

File:

PDF, 431 KB

1978

11

Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation

Lester T. May, Gabriella Torcia, Federico Cozzolino, Anuradha Ray, Stephen B. Tatter, Uma Santhanam, Pravinkumar B. Sehgal, David Stern

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 942 KB

english, 1989

12

SYNTHESIS, STRUCTURE, AND FUNCTION OF POLY(I) · POLY(C)-INDUCED HUMAN FIBROBLAST INTERFERON mRNA

Pravinkumar B. Sehgal, Igor Tamm

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 433 KB

english, 1980

13

Increased Nuclease Sensitivity of the Human Interferon-α 1 -Relate Genes and the Interferon-β 1 Gene During Induction by Virus

SAGAR, ANURAG D., MAY, LESTER T., SEHGAL, PRAVINKUMAR B.

Journal:

Journal of Interferon Research

Year:

1985

Language:

english

File:

PDF, 6.84 MB

english, 1985

14

Interferon-β-related DNA on human chromosome 4

Anurag D. Sagar, Pravinkumar B. Sehgal, Lester T. May, Doris L. Slate, Lester Shulman, Peter E. Barker, Frank H. Ruddle

Journal:

Somatic Cell and Molecular Genetics

Year:

1985

Language:

english

File:

PDF, 576 KB

english, 1985

15

Regulation of the stability of human β interferon mRNA in poly(I)·poly(C)-induced diploid fibroblasts: Anchorage independence of the shutoff mechanism

Pravinkumar B. Sehgal

Journal:

Year:

1981

Language:

english

File:

PDF, 685 KB

english, 1981

16

The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin-6, and Gram stain in patients with preterm labor and intact membranes

Romero, Roberto, Yoon, Bo Hyun, Mazor, Moshe, Gomez, Ricardo, Diamond, Michael P., Kenney, John S., Ramirez, Marcelo, Fidel, Paul L., Sorokin, Yoram, Cotton, David, Sehgal, Pravinkumar

Journal:

American Journal of Obstetrics and Gynecology

Year:

1993

Language:

english

File:

PDF, 1.63 MB

english, 1993

17

Achieving a Desired Esthetic Outcome for a Single-Tooth Implant Restoration with Tissue Excess Using a Multidisciplinary Treatment Approach: A Clinical Report

Ankur Gupta, Rajat Sehgal, Mohana Tagore, Pravinkumar G. Patil, Bhavesh Kothari, Santosh Puri

Journal:

Journal of Prosthodontics

Year:

2011

Language:

english

File:

PDF, 623 KB

english, 2011

18

Interleukin-6 and 12-O-tetradecanoyl Phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells

Tamm, Igor, Cardinale, Irma, Sehgal, Pravinkumar B.

Journal:

Year:

1991

Language:

english

File:

PDF, 6.66 MB

english, 1991

19

[Part 1: Biological Sciences] || Isolation of Novel Human Genomic DNA Clones Related to Human Interferon-β1cDNA

Pravinkumar B. Sehgal, Lester T. May, Anurag D. Sagar, K. Steven LaForge and Masayori Inouye

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.38 MB

english, 1983

20

A Mouse Model for Investigating the Molecular Pathogenesis of Adenovirus Pneumonia

Harold S. Ginsberg, Lyle L. Moldawer, Pravinkumar B. Sehgal, Miriam Redington, Patricia L. Kilian, Robert M. Chanock and Gregory A. Prince

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

21

Regional localization of the interferon-β2B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21

Ferguson-Smith, Anne C., Chen, Yi-Feng, Newman, Marilyn S., May, Lester T., Sehgal, Pravinkumar B., Ruddle, Frank H.

Journal:

Year:

1988

Language:

english

File:

PDF, 2.91 MB

english, 1988

22

Anti-β -interferon Antibodies Inhibit the Increased Expression of HLA-B7 mRNA in Tumor Necrosis Factor-Treated Human Fibroblasts: Structural Studies of the β2Interferon Involved

Lester T. May, David C. Helfgott and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.02 MB

english, 1986

23

Significance of Similarities in Patterns: An Application to β Interferon-Related DNA on Human Chromosome 2

Lester T. May, Frank R. Landsberger, Masayori Inouye and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 962 KB

english, 1985

24

Superinduction of human fibroblast interferon production: Further evidence for increased stability of interferon mRNA

Pravinkumar B. Sehgal, Douglas S. Lyles, Igor Tamm

Journal:

Year:

1978

Language:

english

File:

PDF, 1.14 MB

english, 1978

25

Interleukin-1 and Interleukin-6 Synergize to Increase Plasma Amyloid P and C3 Concentrations in the Mouse

LYLE L. MOLDAWER, E. DIANE BUSHMAN, ANNABEL BARBER, MICHAEL A. MARANO, CHRISTOPHER KEOGH, YUMAN FONG, DAVID C. HELFGOTT, LESTER T. MAY, PRAVINKUMAR SEHGAL, STEPHEN F. LOWRY

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 174 KB

english, 1989

26

Activation of the Human ``β2-Interferon/Hepatocyte-Stimulating Factor/Interleukin 6'' Promoter by Cytokines, Viruses, and Second Messenger Agonists

Anuradha Ray, Stephen B. Tatter, Lester T. May and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.51 MB

english, 1988

27

Multiple Forms of Human Interleukin-6 : Phosphoglycoproteins Secreted by Many Different Tissues

LESTER T. MAY, UMA SANTHANAM, STEPHEN B. TATTER, JOHN GHRAYEB, PRAVINKUMAR B. SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 427 KB

english, 1989

28

The inhibition of DRB (5,6-dichloro-1-β-d-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells

Sehgal, Pravinkumar B., Darnell Jr., James E., Tamm, Igor

Journal:

Year:

1976

Language:

english

File:

PDF, 588 KB

english, 1976

29

Interleukin-1 Can Inhibit Interferon-β Synthesis and Its Antiviral Action: Comparison with Tumor Necrosis Factor

KOHASE, MASAYOSHI, ZHANG, YIHONG, LIN, JIAN-XIN, YAMAZAKI, SHUDO, SEHGAL, PRAVINKUMAR B., VILČEK, JAN

Journal:

Journal of Interferon Research

Year:

1988

Language:

english

File:

PDF, 3.97 MB

english, 1988

30

Dexamethasone inhibits feedback regulation of the mitogenic activity of tumor necrosis factor, interleukin-1, and epidermal growth factor in human fibroblasts

Dr. Masayoshi Kohase, Dorothy Henriksen-Destefano, Pravinkumar B. Sehgal, Jan Vilĉek

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 900 KB

english, 1987

31

Rapid Enhancement of β2-interferon/B-cell Differentiation Factor BSF-2 Gene Expression in Human Fibroblasts by Diacylglycerols and the Calcium Ionophore A23187

Pravinkumar B. Sehgal, Zenta Walther and Igor Tamm

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.22 MB

english, 1987

32

Interleukin-6 Enhances Motility of Breast Cancer Cells

Sehgal, Pravinkumar B., Tamm, Igor

Journal:

Cancer Investigation

Year:

1990

Language:

english

File:

PDF, 381 KB

english, 1990

33

Heterogeneity of poly(I).poly(C)-induced human fibroblast interferon mRNA species

Sehgal, Pravinkumar B., Sagar, Anurag D.

Journal:

Year:

1980

File:

PDF, 364 KB

1980

34

Phosphorylation of secreted forms of human β2-interferon/hepatocyte stimulating factor/interleukin-6

Lester T. May, Uma Santhanam, Stephen B. Tatter, Nina Bhardwaj, John Ghrayeb, Pravinkumar B. Sehgal

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 1.34 MB

english, 1988

35

Cytokine-induced Production of IL-6 by Freshly Explanted Human Endometrial Stromal Cells : Modulation by Estradiol-17β

SIAMAK S. TABIBZADEH, UMA SANTHANAM, LESTER MAY, PRAVINKUMAR SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 77 KB

english, 1989

36

Signal Transduction Pathways in the Induction of 2′, 5′-oligoadenylate Synthetase Gene Expression by Interferon α /β

Cong Yan, Pravinkumar B. Sehgal and Igor Tamm

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1011 KB

english, 1989

37

Does 3′-Terminal Poly(A) Stabilize Human Fibroblast Interferon mRNA in Oocytes of Xenopus laevis?

Pravinkumar B. Sehgal, Hermona Soreq and Igor Tamm

Journal:

Proceedings of the National Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 602 KB

english, 1978

38

On the Relationship Between Human Interferon α 1 and β 1 Genes

MAY, LESTER T., SEHGAL, PRAVINKUMAR B.

Journal:

Journal of Interferon Research

Year:

1985

Language:

english

File:

PDF, 2.26 MB

english, 1985

39

Repression of the Interleukin 6 Gene Promoter by p53 and the Retinoblastoma Susceptibility Gene Product

Uma Santhanam, Anuradha Ray and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.06 MB

english, 1991

40

Role of interleukin-6 in regulating synthesis of C-reactive protein and serum amyloid A in human hepatoma cell lines

Mahrukh K. Ganapathi, Lester T. May, Debra Schultz, Anne Brabenec, Joel Weinstein, Pravinkumar B. Sehgal, Irving Kushner

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 516 KB

english, 1988

41

[Part 1: Biological Sciences] || Unusually Long mRNA Species Coding for Human α and β Interferons

Pravinkumar B. Sehgal, Lester T. May, K. Steven LaForge and Masayori Inouye

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.46 MB

english, 1982

42

Expression of Retrovirally Transduced IL-1 α in IL-6-Dependent B Cells: A Murine Model of Aggressive Multiple Myeloma

Hawley, Teresa S., Lach, Boleslaw, Burns, Bruce F., May, Lester T., Sehgal, Pravinkumar B., Hawley, Robert G.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.23 MB

english, 1991

43

Primary Structural Repeats in Human and in Murine γ-Interferon

SEHGAL, PRAVINKUMAR B., MAY, LESTER T., LANDSBERGER, FRANK R.

Journal:

Journal of Interferon Research

Year:

1986

Language:

english

File:

PDF, 411 KB

english, 1986

44

Interleukin 6 is Expressed in High Levels in Psoriatic Skin and Stimulates Proliferation of Cultured Human Keratinocytes

Rachel M. Grossman, James Krueger, Debra Yourish, Angela Granelli-Piperno, Daniel P. Murphy, Lester T. May, Thomas S. Kupper, Pravinkumar B. Sehgal and Alice B. Gottlieb

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.22 MB

english, 1989

45

Rapid detection and sequencing of alleles in the 3′ flanking region of the Interleukin-6 gene

Bowcock, Anne M., Ray, Anuradha, Erlich, Henry, Sehgal, Pravinkumar B.

Journal:

Nucleic Acids Research

Year:

1989

Language:

english

File:

PDF, 1.79 MB

english, 1989

46

DNA Methylation and the Expression of Human Interferon Alpha-1-Related Genes and the Beta-I Gene

SAGAR, ANURAG D., MAY, LESTER T., SEHGAL, PRAVINKUMAR B.

Journal:

Journal of Interferon Research

Year:

1983

Language:

english

File:

PDF, 2.99 MB

english, 1983

47

THE RELATIONSHIP OF SERUM IL-6 LEVELS TO ACUTE GRAFT-VERSUS-HOST DISEASE AND HEPATORENAL DISEASE AFTER HUMAN BONE MARROW TRANSPLANTATION

SYMINGTON, FRANK W., SYMINGTON, BANU E., LIU, P. Y., VIGUET, HUGUETTE, SANTHANAM, UMA, SEHGAL, PRAVINKUMAR B.

Journal:

Transplantation Journal

Year:

1992

File:

PDF, 623 KB

1992

48

Identification and Characterization of Interleukin-6/Interferon-β2 in Synovial Effusions of Patients with Rheumatoid Arthritis and Other Arthritides

NINA BHARDWAJ, UMA SANTHANAM, LISA L. LAU, STEPHEN B. TATTER, JOHN GHRAYEB, MARCOS RIVELIS, RALPH M. STEINMAN, PRAVINKUMAR B. SEHGAL, LESTER T. MAY

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 94 KB

english, 1989

49

[Part 2: Biological Sciences] || Regulation of the Stability of Poly(I)· Poly(C)-Induced Human Fibroblast Interferon mRNA: Selective Inactivation of Interferon mRNA and Lack of Involvement of 2′,5′-oligo(A) Synthetase Activation during the Shutoff of Interferon Production

Pravinkumar B. Sehgal and Sohan L. Gupta

Journal:

Proceedings of the National Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 900 KB

english, 1980

50

Two mechanisms contribute to the superinduction of poly(I)·poly(C)-induced human fibroblast interferon production

Pravinkumar B. Sehgal, Igor Tamm

Journal:

Year:

1979

Language:

english

File:

PDF, 403 KB

english, 1979

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